This study was meant to discern the level of interest in sex-related topics of 6th graders in order to better shape the type of health education they receive. The study looked into whether the results differed in co-ed schools versus single-sex environments in addition to whether the results were influenced by school-level sexual risk. Some of the themes that came up most often within the study were sexual activity, female anatomy, reproduction, and puberty. The study found that students in lower sexual-risk schools tended to avoid sexual topics in questions, while students in higher risk did not. Additionally, questions asked by students of single-sex schools tended to be more direct and explicit than those from students attending co-ed schools. This study is important for educators and healthcare providers who early adolescents often turn to with questions regarding sexual health.