Ongoing since 2009

Project Director: Tracy Gladstone, Ph.D.

Funder: The National Institute of Mental Health (NIMH) with the Judge Baker Children's Center

The research teamwill examine the long-term effects of an earlier intervention on preventing depression during the critical developmental transition to young adulthood.

The Prevention of Depression project is a four-site effectiveness study being conducted at Judge Baker Children's Center (JBCC), Vanderbilt University, the University of Pittsburgh, and the Center for Health Research at Kaiser Permanente in Portland, Oregon. In the initial phase of this research, Gladstone and colleagues recruited 316 at-risk teens, ages 13-17, who were assigned randomly to participate in a Cognitive Behavioral Prevention (CBP) or Usual Care (UC) condition. In the current, follow-up study, Gladstone and colleagues will examine the long-term effects of the CBP intervention on preventing depression during the critical developmental transition to young adulthood, and will assess potential biological and psychosocial moderators of intervention response. The project also will examine the longer term cost-effectiveness of the CBP.